Fu Zheng Xiao Yu San Jie Decoction affects the proliferation of renal cell carcinoma via regulating <i>E2F5</i> gene.

ABSTRACT:

Background

Renal cell carcinoma (RCC) is a prevalent disease within the urinary system, characterized by high mortality rates. Its incidence is increasing each year, posing a significant threat to public health. Currently, the causes of RCC are not fully understood, and there are many limitations in treatment options. Recently, traditional Chinese medicine has gained considerable attention in cancer treatment. Fu Zheng Xiao Yu San Jie Decoction (FZXYSJD) is a well-established treatment for RCC, used for many years at The First Affiliated Hospital of Guangzhou University of Chinese Medicine, and is recognized for its efficacy by both physicians and patients. This study aims to employ methods such as network pharmacology and cell experiments to investigate how FZXYSJD works in treati

SUBMITTER: Liang A 

PROVIDER: S-EPMC12779431 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature