Focal irreversible electroporation for the treatment of localised prostate cancer: a systematic review.

ABSTRACT:

Background

Focal irreversible electroporation (IRE) has shown promising initial oncological and functional outcomes in the treatment of localised prostate cancer (PCa), although robust evidence to support its efficacy and optimal utilisation is still maturing. We aim to summarise the oncological outcomes, functional outcomes, and safety profile of IRE for the treatment of localised PCa.

Methods

A search was performed across four electronic databases: MEDLINE, Embase, Web of Science, and Cochrane Database of Systematic Reviews; 620 articles were screened after removal of duplicates; 73 full-texts were reviewed.

Results

Thirty-one articles representing 29 studies were included. Focal IRE patients ranged from 10 to 411 patients. Median follow-up ranged from 6 to 60 month

SUBMITTER: Cheng J 

PROVIDER: S-EPMC12779442 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature