Quantitative summarization of high-touch surfaces and epidemiological parameters of <i>Clostridioides difficile</i> acquisition and transmission for mathematical modeling: a systematic review.

ABSTRACT:

Objective

The study aimed to summarize estimates of key epidemiological parameters to improve the effectiveness of Clostridioides difficile infection (CDI) mathematical models and quantitatively characterize high-touch surfaces (HTSs) and mutual-touch surfaces in healthcare settings.

Methods

We systematically searched four databases and applied predefined eligibility criteria to screen, select, and include peer-reviewed studies in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The study is registered in the International Prospective Register of Systematic Reviews (CRD42023408483).

Results

Among the 21 C. difficile infection modeling studies, 76.2% used compartmental model approaches that group patients

SUBMITTER: Olufadewa I 

PROVIDER: S-EPMC12779462 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature