Changing trends in drug overdose mortality in Spain, 2001-2022.

ABSTRACT:

Aim

To measure the evolution of drug overdose mortality in Spain between 2001 and 2022.

Design, setting, participants

A repeated cross-sectional observational study using nationwide mortality data from Spain, 2001-2022, among individuals aged 15-64 years.

Measurements

The outcome was overdose deaths [International Classification of Diseases, 10th revision (ICD-10) codes: X40-X44, X60-X64, X85, Y10-Y14]. Annual age-standardized mortality rates (ASMRs) per million person-years were estimated. Joinpoint regression assessed changes in trends using annual percentage change (APC) and average APC (AAPC). Overdose deaths were grouped by the underlying drug categories involved: nonopioid analgesics, antipyretics and antirheumatics (X40/X60/Y10); antiepileptic, sedative-hypnoti

SUBMITTER: Gine F 

PROVIDER: S-EPMC12779592 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature