Performance evaluation of the nanoScan^® P123S total-body PET.

ABSTRACT:

Purpose

Before utilising preclinical Position Emission Tomography (PET) systems for biological studies, evaluating their performance is important to better qualify the scanner's applications. This study aims to assess the performance of the new extended field of view (FOV) nanoScan® PET/CT P123S system, developed for rodent total-body PET applications.

Methods

Scanner resolution, noise equivalent count rate (NECR), sensitivity and image quality were evaluated following NEMA NU-4 2008 protocols. Furthermore, a Derenzo phantom and linearity measurements were conducted. In vivo studies were subsequently carried out to evaluate system performance in biological applications.

Results

The scanner spatial resolution according to the NEMA protocol was 1.4 mm using FBP reconstr

SUBMITTER: Reti D 

PROVIDER: S-EPMC12779859 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature