Trends and disparities in obesity and atherosclerotic cardiovascular disease mortality in a 25-year retrospective analysis.

ABSTRACT: Obesity is a major risk factor for atherosclerotic cardiovascular disease (ASCVD) and contributes significantly to mortality in the US. We analyzed national mortality trends in obesity-related ASCVD mortality (1999-2023). Age-adjusted mortality rates (AAMRs), crude mortality rates (CMRs), average annual percent change (AAPC), and annual percent change (APC) were calculated per 100,000 population using Joinpoint regression. From 1999 to 2023, a total of 267,315 deaths were attributed to obesity and ASCVD. The AAMR increased from 2.45 in 1999 to 7.23 in 2023, reflecting an overall AAPC of 4.67 (95% CI: 4.05-5.29). The most significant rise occurred between 2018 and 2021 (APC: 14.67, 95% CI: 9.90-19.66). Males had a higher overall AAMR (5.26) compared to females (3.11). By race, Blacks experi

SUBMITTER: Parvez A 

PROVIDER: S-EPMC12780052 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature