Flagellin recognition triggers zinc mobilization in Arabidopsis thaliana as a response to Salmonella Typhimurium invasion.

ABSTRACT: Salmonella enterica serovar Typhimurium can enter and colonize the apoplast of plants, including the edible ones, making them a potential reservoir for the pathogen and a route for human contamination. We previously showed that in Arabidopsis thaliana shoot colonization, S. Typhimurium takes advantage of its ability to export zinc primarily through the P_1B-type ATPase ZntA induced by zinc excess. Moreover, a plant line with reduced ability to translocate zinc from roots to shoots is more susceptible to S. Typhimurium shoot colonization. We, therefore, hypothesized that plants employ zinc intoxication as a defense strategy against invading bacteria. Here we show that, upon S. Typhimurium colonization, A. thaliana modulates the expression of zinc transporters, favoring the long-di

SUBMITTER: Mandava TA 

PROVIDER: S-EPMC12780153 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature