Synthesis, spectral, thermal, and biological characterization of Se(IV) nanocomplexes derived from vitamin E and amino acid mixed ligands as a metal-drug model.

ABSTRACT: Researchers have been interested in inorganic pharmaceutical chemistry in recent years. They have prepared antioxidants and anticancer compounds to lower the cost of manufacturing platinum and palladium medications and as alternatives to some known side-effect drugs. The current work focused on selenium complexes with mixed ligands, which included histidine, tryptophan, and tyrosine as the second ligand and one of the interesting vitamins, like vitamin E, as the first ligand. The synthesis was done in a molar ratio of (1:2:1) (selenium: vitamin E: amino acid). Different characterization techniques were used to check and discuss the chemical structures and morphological properties of the synthesized complexes, including elemental analysis, conductance, FTIR, XRD, UV-Vis, TG/DTG, ¹

SUBMITTER: El-Sayed MY 

PROVIDER: S-EPMC12780159 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature