Phylogenomic profile of exon-intron organization across angiosperms, their relationships with protein domains, and functional implications.

ABSTRACT: Eukaryotic genes usually encode proteins and contain exons in different size, including micro and small exon categories. However, genome-wide gene exon-intron organizations and their conservation across angiosperms have not been investigated. Among exons of protein-coding genes from 46 angiosperms and four gymnosperms, ~35% are micro and small exons affecting most genes and the remaining exons are defined here as medium, large, or super exons. Exon-intron structural comparison using our new bioinformatic tool, ExonEvo, reveals that, ~69% of conserved exons in homologous genes are found in two or more major angiosperm subgroups, including ~47% as the seed plant-wide conserved exons that are present in most genes in individual species. An examination of domain-exon correspondence revealed th

SUBMITTER: Zhang T 

PROVIDER: S-EPMC12780178 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature