Coronary CT Angiography-Derived Fractional Flow Reserve in Asia and the United States: 2025 Status Update.

ABSTRACT: Coronary CT-derived fractional flow reserve (CT-FFR) is a noninvasive alternative to invasive FFR for assessing the hemodynamic significance of coronary artery stenosis. CT-FFR uses routinely acquired coronary CT angiography (CCTA) with artificial intelligence and computational fluid dynamics to estimate pressure gradients, thereby supporting clinical decision-making without procedural risk. Adoption and implementation vary widely across regions. In Asia, South Korea exclusively uses HeartMedi+, which enables rapid analysis, streamlined workflow integration, and high user satisfaction. Japan relies primarily on FFR_CT, which has national reimbursement and significantly influences treatment strategies, reducing unnecessary invasive procedures. Hong Kong, Singapore, Taiwan, Thailan

SUBMITTER: Ahn WJ 

PROVIDER: S-EPMC12780370 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature