Segmentectomy versus lobectomy for stage I non-small cell lung cancer: a real-world propensity score-matched analysis.

ABSTRACT:

Background

Although lobectomy is considered the standard surgical treatment for stage I non-small cell lung cancer (NSCLC). Recently, anatomical segmentectomy may represent an acceptable oncologic option for these patients. The study aims to compare perioperative and long-term outcomes between anatomical segmentectomy and lobectomy for stage I NSCLC using propensity score matching (PSM) in a single thoracic surgery centre.

Methods

We retrospectively analyzed 60 patients with stage I NSCLC who underwent pulmonary resection between 2017-2024. After 1:1 PSM, 50 patients (25 per group) were included. All patients underwent radical lymphadenectomy with ≥3 mediastinal stations dissected. Primary endpoints were overall survival (OS) and disease-free survival (DFS). Secondary endpoi

SUBMITTER: Kanani F 

PROVIDER: S-EPMC12780387 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature