Corticosteroid use before ICU admission and 90-day all-cause readmission risk in patients with acute exacerbation of chronic obstructive pulmonary disease: an analysis of the MIMIC-IV database.

ABSTRACT:

Background

Patients experiencing acute exacerbation of chronic obstructive pulmonary disease (AECOPD) often face poor prognoses and high readmission rates. While corticosteroids play a central role in the management of AECOPD by reducing airway inflammation, improving lung function, and accelerating symptom resolution, their impact on subsequent readmission risk in AECOPD patients remains unclear. This study aimed to explore the relationship between corticosteroid use prior to intensive care unit (ICU) admission and the 90-day all-cause readmission risk in AECOPD patients.

Methods

We included 1,219 AECOPD patients from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. To balance baseline characteristics between groups, we employed inverse probability of

SUBMITTER: Jiang C 

PROVIDER: S-EPMC12780399 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature