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A predictive model for postoperative compensatory hyperhidrosis in primary palmar hyperhidrosis: a retrospective cohort study.


ABSTRACT:

Background

While sympathectomy remains the optimal surgical intervention for severe primary palmar hyperhidrosis (PPH), compensatory hyperhidrosis (CH) has emerged as the most significant factor contributing to postoperative patient regret. This retrospective study aimed to identify risk factors and develop a predictive model for moderate-to-severe compensatory hyperhidrosis (msCH) in patients with PPH.

Methods

A total of 1,013 patients were retrieved from the institutional database between 2014 and 2024. Logistic regression modeling was utilized to identify risk factors for msCH. A nomogram for predicting msCH was developed accordingly.

Results

Of the initial cohort, there were 903 patients included in the final analysis, among whom 182 (20.2%) developed msCH. The fo

SUBMITTER: Luo P 

PROVIDER: S-EPMC12780405 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature