Postoperative routine computed tomography allows detection of early-stage acute exacerbations of interstitial pneumonia.

ABSTRACT:

Background

Postoperative acute exacerbation of interstitial pneumonia (IP-AE) is highly lethal after lung resection. Whether a symptom-free, routine computed tomography (rCT) can detect IP-AE early enough to justify pre-emptive steroids is unknown. We therefore aimed to assess the diagnostic accuracy of early postoperative rCT for detecting clinical IP-AE (cIP-AE) and to identify a high-specificity rCT score threshold that could support pre-emptive steroid treatment.

Methods

This single-center, retrospective diagnostic-accuracy study analyzed 120 consecutive lung-cancer patients with underlying interstitial pneumonia (IP) who underwent high-resolution rCT within 7 days after surgery. Eligibility was based on preoperative high-resolution computed tomography (HRCT) demonstrati

SUBMITTER: Seto K 

PROVIDER: S-EPMC12780451 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature