Development of a predictive model for lymph node metastasis in esophageal cancer using ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) semi-quantitative parameters and tumor biomarkers.

ABSTRACT:

Background

To explore the value of semi-quantitative parameters of ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) combined with tumor markers in predicting lymph node metastasis (LNM) in esophageal cancer (EC). This study aimed to explore the value of ¹⁸F-FDG PET/CT semi-quantitative parameters combined with tumor markers in predicting EC-related LNM.

Methods

A retrospective analysis was conducted on 200 pathologically confirmed EC patients (157 with LNM, 43 without LNM) who underwent preoperative ¹⁸F-FDG PET/CT. Inclusion criteria: no prior anticancer treatment, complete clinical/imaging/tumor marker data. LNM was confirmed by postoperative pathological examination. PET/CT parameters such

SUBMITTER: Li N 

PROVIDER: S-EPMC12780565 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature