Trends of mortality among patients with malignant neoplasms of digestive system in the United States from 2007 to 2021.

ABSTRACT:

Background

While malignant neoplasms (MNs) of digestive system (MNDS) remain a leading cause of cancer mortality, evolving patterns of cause-specific deaths in the modern treatment era are poorly characterized. This study aimed to depict the trends in cause-specific mortality among MNDS patients in the U.S. from 2007 to 2021, stratified by clinical and demographic factors, with particular focus on the growing impact of non-neoplasm causes of death (CODs).

Methods

This retrospective study analyzed incidence-based mortality rates from 22 registries of the Surveillance, Epidemiology, and End Results program. Patients diagnosed with MNDS in 2000-2021 who died in 2007-2021 were included. Mortality rates were age-adjusted to the 2000 U.S. standard population. Trends of mortality r

SUBMITTER: Hua Y 

PROVIDER: S-EPMC12780590 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature