Echocardiography-derived pulmonary vascular resistance outperforms coagulation profiles and thromboelastography in predicting in-hospital mortality among surgical intensive care unit patients.

ABSTRACT:

Background

Patients in the surgical intensive care unit (SICU) frequently present with coagulation disorders and cardiopulmonary interaction disturbances. This study aimed to examine alterations in coagulation status and pulmonary vascular resistance (PVR), and compare their predictive efficacy for in-hospital mortality in this population.

Methods

In this prospective observational study (January 2025 to April 2025), 61 consecutive SICU patients were enrolled and stratified into survivors (n=43) and non-survivors (n=18). Comprehensive echocardiographic assessments were performed to quantify PVR. Coagulation test and thromboelastography (TEG) were used to monitor coagulation status. Multivariable logistic regression identified independent predictors of in-hospital mortality.

SUBMITTER: Wu X 

PROVIDER: S-EPMC12780594 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature