Functional connectivity in electroencephalography of brain tumor patients in status epilepticus: a retrospective evaluation of prognostic value.

ABSTRACT:

Background

There is currently no individualized prognostic tool to predict outcomes in patients with brain tumors following status epilepticus (SE), despite its clinical importance for counseling and therapeutic decision-making. This proof-of-principle, retrospective monocentric study investigated whether electroencephalography (EEG)-derived functional connectivity patterns differ in brain tumor patients after SE with respect to survival and tumor type.

Methods

EEG data from 37 brain tumor patients with SE were analyzed. Thirty epochs per frequency band (delta-gamma) were selected using spectral power. Source-space connectivity was measured via weighted Phase Lag Index (wPLI). Permutation tests compared connectivity between survival (>1 vs. <1 year) and tumor subgroup

SUBMITTER: Kuba P 

PROVIDER: S-EPMC12780627 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature