Genetic and Environmental Associations Among Pain, Sleep Disturbances, and Substance Use Intent in Early Adolescence.

ABSTRACT:

Purpose

Pain, sleep disturbances, and substance use are common in adolescence, with research indicating that genetic and environmental factors account for variation in each of these behavioral and health outcomes. Moreover, pain, sleep disturbances, and substance use often co-occur during adolescence. However, research has not examined whether there is genetic and/or environmental covariation across these constructs in early adolescence or in diverse samples. To address these gaps, we examined genetic and environmental covariation in pain, sleep disturbances, and substance use intent in early adolescence.

Methods

Our study used data from the Adolescent Brain Cognitive Development (ABCD) twin subsample at age 12/13 (834 monozygotic twins (MZ) and 1262 dizygotic (DZ) twins; 50

SUBMITTER: Elam KK 

PROVIDER: S-EPMC12780654 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature