Native T1-rho mapping for myocardial scar detection in patients with probable or confirmed coronary artery disease.

ABSTRACT:

Background

T1rho cardiac mapping is an emerging, non-contrast magnetic resonance imaging (MRI) technique sensitive to myocardial biochemical and microstructural changes, whereas late gadolinium enhancement (LGE) remains the reference standard for scar visualization, though its reliance on contrast agent limits its applications and raises safety and environmental concerns. This study aimed to evaluate native T1-rho (T1ρ) mapping in detecting myocardial scars, compared with the gold standard LGE method.

Methods

A prospective study was conducted, including patients with suspected or known coronary artery disease (CAD). In addition to adenosine stress cardiac magnetic resonance (CMR) and LGE, native T1ρ mapping was performed. T1ρ-weighted images were acquired at the mid-left ven

SUBMITTER: Prapan N 

PROVIDER: S-EPMC12780665 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature