Ultra-high contrast MRI of the brain and spinal cord using directly acquired and synthetic BipoLAr Inversion Recovery (BLAIR) images.

ABSTRACT: Ultra-high contrast (UHC) magnetic resonance imaging (MRI) is a term used to describe magnetic resonance (MR) imaging that shows abnormalities with high contrast when little or no abnormality is seen on common conventional state-of-the-art MR images. It is achieved without the use of increased static or gradient magnetic fields. UHC can be accomplished by using tissue properties such as T₁ and T₂ twice or more in the same sequence. This synergistically contributes to overall contrast as with directly acquired divided subtracted inversion recovery (dSIR) T₁-BipoLAr Inversion Recovery (BLAIR) sequences. These sequences can also provide high contrast and high spatial resolution signal boundaries. UHC MRI can also be achieved by applying synthetic bipolar filte

SUBMITTER: Cornfeld DM 

PROVIDER: S-EPMC12780704 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature