Improvement in coronary microvascular dysfunction after transcatheter aortic valve implantation leading to positive fractional flow reserve and percutaneous coronary intervention: a case report.

ABSTRACT:

Background

The management of coronary artery disease in patients with severe aortic stenosis is controversial, with no consensus on optimal revascularization strategies. The validity of using fractional flow reserve to assess ischaemia in this population is debated. Conflicting results have arisen regarding the impact of transcatheter aortic valve implantation on fractional flow reserve values. We present the case of a patient with severe aortic stenosis and intermediate left anterior descending artery stenosis, in whom the fractional flow reserve and the index of microcirculatory resistance suggested the presence of coronary microvascular dysfunction prior to transcatheter aortic valve implantation. However, after valve replacement, the fractional flow reserve and the index of mic

SUBMITTER: Fujita K 

PROVIDER: S-EPMC12780881 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature