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ABSTRACT: Background
Sick sinus syndrome often necessitates permanent pacemaker implantation; however, when sinus node artery ischaemia is the cause, sinus node dysfunction may be reversible. While age-related fibrosis is generally considered the main mechanism, ischaemia should also be recognized as a potential aetiology.Case summary
An 80-year-old woman with breast cancer, hypertension, and diabetes mellitus presented with dyspnoea. Electrocardiography showed marked bradycardia at 38 beats per minute (b.p.m.) without ST-segment changes. Chest radiography revealed a cardiothoracic ratio of 61% with mild pulmonary congestion, and echocardiography showed preserved left ventricular ejection fraction (>60%) without wall motion abnormality. Although referred for pacemaker implantation, t
SUBMITTER: Kaneko Y
PROVIDER: S-EPMC12780886 | biostudies-literature | 2026 Jan
REPOSITORIES: biostudies-literature