Risk and prognosis of colorectal cancer following bacteraemia with <i>Streptococcus bovis</i>-<i>Streptococcus equinus</i> complex: A Swedish nationwide retrospective cohort study.

ABSTRACT: There is a positive association between bacteraemia with Streptococcus bovis-Streptococcus equinus complex (SBSEC) and colorectal cancer (CRC). However, the relationship between the timing of SBSEC bacteraemia and CRC is not well-established. Associations with other gastrointestinal cancers have also been suggested. Using national registries, we retrospectively examined the incidence of CRC and other gastrointestinal cancers after SBSEC-bacteraemia in Sweden 2010-2019, and analysed the timing, characteristics, and prognosis of diagnosed CRC. Individuals with SBSEC-bacteraemia were matched to randomly selected controls from the general population at a 1:10 ratio. Cox-regression determined CRC hazard ratios (HR). In total, 908 individuals with SBSEC-bacteraemia were identified and 9,0

SUBMITTER: Oberg J 

PROVIDER: S-EPMC12780919 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature