Social Determinants of Health and Clinical Outcomes in Hypertrophic Cardiomyopathy.

ABSTRACT:

Importance

Area-based indicators of social determinants of health (SDOH) are associated with higher risk for acquired heart disease, but their impact on conditions with a strong genetic etiology, such as hypertrophic cardiomyopathy (HCM), is not well understood.

Objective

To determine the association of area-based SDOH with clinical outcomes in patients with HCM.

Design, setting, and participants

This multicenter, prospective cohort study was conducted among US adult patients with HCM from 5 sites in the Sarcomeric Human Cardiomyopathy Registry (a multicenter prospective registry of patients with HCM) who were followed up for a median (IQR) period of 2.15 (0.15-5.82) years. Data were entered from 2015 to March 2024, and data analysis was completed from March 2024 to J

SUBMITTER: Hafeez N 

PROVIDER: S-EPMC12780983 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature