Meta-Analysis of Durable Compared to Temporary Left Ventricular Assist Devices Compared to Venoarterial Extracorporeal Membrane Oxygenation for Bridging to Heart Transplantation or Treatment of Primary Graft Dysfunction.

ABSTRACT:

Background

Patients bridged to heart transplantation (HTx) and patients with primary graft dysfunction (PGD) after HTx are typically treated with circulatory support. However, the survival of patients in both indications might depend on the type of circulatory support. Thus, this meta-analysis aimed to investigate the survival of HTx patients supported during bridging with a durable left ventricular assist device (d-LVAD), a temporary LVAD (t-LVAD), or venoarterial extracorporeal membrane oxygenation (VA-ECMO). We also investigated the survival rate of patients with PGD by type of circulatory support device.

Methods

We performed a random-effects meta-analysis.

Results

We included four studies evaluating bridging to HTx (n = 1678 patients) and three studies for the PGD

SUBMITTER: Saemann L 

PROVIDER: S-EPMC12780990 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature