Association Between the Duration of Elevated Perfusion Pressure and Neurological Outcomes in Out-of-Hospital Cardiac Arrest Survivors.

ABSTRACT:

Background

The association between elevated perfusion pressure and neurological outcomes in out-of-hospital cardiac arrest (OHCA) survivors remains unclear. Specifically, to our knowledge, no studies have currently investigated whether the duration of elevated perfusion pressure influences neurological prognosis following OHCA. Thus, this study aimed to examine the association between the duration of a mean arterial pressure (MAP) >80 mmHg during the first 48 hours after return of spontaneous circulation (ROSC) and neurological outcomes in OHCA survivors.

Methods

This observational study included adult patients (≥18 years) with OHCA treated between January 2019 and May 2021. The cumulative duration of a MAP >80 mmHg was recorded during the 0-24, 25-48, and 0-48 hour interval

SUBMITTER: Lee DH 

PROVIDER: S-EPMC12780993 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature