Beta-Blockers in Stable Coronary Artery Disease: A Systematic Review and Meta-Analysis of Observational Studies.

ABSTRACT:

Background

The efficacy of beta-blockers in stable coronary artery disease (CAD) patients with preserved left ventricular function remains controversial. We aimed to evaluate the cardiovascular associations of beta-blocker therapy in this population through a comprehensive meta-analysis.

Methods

We conducted a systematic review and meta-analysis following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, searching PubMed, EMBASE, Web of Science, Scopus, Google Scholar, and Cochrane databases from inception to May 2025, updating and extending the previous meta-analysis. We included observational studies comparing beta-blocker therapy versus control in stable CAD patients, defined as those without acute coronary syndrome manifestations for

SUBMITTER: Liu JX 

PROVIDER: S-EPMC12781013 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature