Impact of myocardial perfusion abnormalities on clinical outcomes in patients treated with percutaneous coronary intervention for chronic total occlusions.

ABSTRACT:

Introduction

Myocardial perfusion imaging (MPI) is used to evaluate ischaemia in patients with chronic total occlusion (CTO), but its prognostic implications following percutaneous coronary intervention (PCI) of CTO remain uncertain.

Purpose

To evaluate outcomes in patients treated with CTO-PCI stratified by moderate-severe ischaemia on MPI prior to intervention.

Methods and results

Patients from the Western Danish Heart Registry assessed by nuclear MPI and subsequently treated with CTO-PCI ≤ 6 months were included. Moderate-severe ischaemia was defined as ≥10% left ventricle involvement. Primary endpoints were all-cause mortality and a composite of major adverse cardio- and cerebrovascular events [MACCE; cardiovascular death, myocardial infarction (MI), stroke, and h

SUBMITTER: Henningsen JB 

PROVIDER: S-EPMC12781094 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature