Combined training improves functional capacity, fatigue, and quality of life in individuals with multiple sclerosis: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Multiple Sclerosis (MS) severely affects strength, coordination, gait, and balance, leading to significant challenges for individuals. While exercise is known to benefit MS management, most studies focus on single modalities, leaving a gap in understanding the effects of combined training (CT) interventions. This systematic review aims to address this gap by examining the impact of diverse CT interventions on muscle strength, balance, gait speed, endurance, fatigue, and quality of life in people with MS (PwMS). The findings will provide valuable insights for enhancing rehabilitation strategies tailored to the multifaceted needs of PwMS.

Methods

Primary sources were gathered from eight databases: PubMed, SCOPUS, Embase, EBSCO, CENTRAL (Cochrane Central Register o

SUBMITTER: Kazemi Pakdel F 

PROVIDER: S-EPMC12781395 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature