Association between dietary n-6/n-3 ratio and attention-deficit/hyperactivity disorder among American children and adolescents: findings from the National Health and Nutrition Examination Survey.

ABSTRACT:

Background

Industrialized eating habits have disrupted the balance between n-6 to n-3 polyunsaturated fatty acids, a change reflected in human tissue composition. Increased n-6 to n-3 ratios may contribute to the emergence of several neurodevelopmental conditions. This study aims to determine how the balance between dietary n-6 and n-3 fatty acids relates to attention-deficit/hyperactivity disorder (ADHD) in kids and teenagers in the U.S.

Methods

Data were derived from 5,882 participants aged 4-15 years who participated in the National Health and Nutrition Examination Survey between 1999 and 2004. To examine the connection between dietary n-6 to n-3 fatty acid ratios and ADHD, multivariable logistic regression models were utilized. Additionally, restricted cubic spline model

SUBMITTER: Wang L 

PROVIDER: S-EPMC12781451 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature