Global prevalence and incidence of precocious puberty: a systematic review and meta-analysis.

ABSTRACT:

Background

The significant rise in precocious puberty rates over recent decades has adversely impacted children's health, spurring numerous epidemiological studies. However, prevalence and incidence estimates vary widely across regions and lack a comprehensive global perspective. Therefore, we estimated the global prevalence and incidence of precocious puberty among children.

Methods

We comprehensively searched PubMed, Embase, and Web of Science from inception to February 2024 for articles reporting the prevalence or incidence of precocious puberty. For studies based on cross-sectional surveys, we used a random-effects model to estimate the pooled prevalence and 95% confidence interval (CI) of precocious puberty in girls and boys. The 95% CI was calculated using the inverse-

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12781560 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature