Effect of percutaneous coronary intervention on chronic total occlusions with documented viability or ischemia: a systematic review and meta-analysis.

ABSTRACT:

Background

Percutaneous coronary intervention (PCI) for chronic total occlusions (CTO) is common despite the equivocal evidence regarding its benefits. This study aimed to evaluate the impact of pre-PCI viability or ischemia assessment on left ventricular (LV) function, ischemic burden, symptoms, and major adverse cardiovascular events in CTO patients.

Methods

A systematic search of PubMed/MEDLINE, EMBASE, CENTRAL, Web of Science Core Collection, ClinicalTrials.eu, and ClinicalTrials.gov was conducted. Studies assessing viability and/or ischemia before PCI with follow-up data were included. Quality was assessed using Cochrane Risk of Bias 2.0 and ROBINS-I tools. Meta-analyses were conducted for quantitative outcomes and narrative synthesis for heterogeneous data. A total of

SUBMITTER: Leite L 

PROVIDER: S-EPMC12781582 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature