Phenolic Profile and In Vitro Anti-Inflammatory Activities of Salvia officinalis L. Hydrodistillation Wastewater.

ABSTRACT: Salvia officinalis L. essential oil production process generates an exhausted residue of vegetable biomass, returned by hydrodistillation, along with a variable amount of wastewater enriched in water-soluble compounds of high added value and biological activity. The aim of this study was to investigate the in vitro anti-inflammatory effects of S. officinalis L. hydrodistillation wastewater using murine macrophage Raw 264.7 cells stimulated with Escherichia coli lipopolysaccharide (LPS) and human intestinal epithelial Caco-2 cells exposed to E. coli. Polyphenolic compounds in wastewater were identified by high-performance liquid chromatography-mass spectrometry analysis, confirming the presence of organic acids (particularly hydroxycinnamic acids), flavones, and flavonols. This phytocomplex

SUBMITTER: Molonia MS 

PROVIDER: S-EPMC12781621 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature