Shortening breath-hold durations in breast radiotherapy: a novel time-control strategy for deep inspiration breath-hold VMAT.

ABSTRACT:

Background

To address the issue where single Volumetric Modulated Arc Therapy (VMAT) delivery times often exceed a patient's comfortable breath-hold capacity of approximately 20s during Deep Inspiration Breath-Hold (DIBH) radiotherapy for breast cancer, this study proposes and systematically evaluates a novel time-control optimization strategy. The goal is to reduce overall delivery time and improve temporal uniformity across individual arcs within the United Imaging Healthcare (UIH) uTPS platform.

Methods

The study included 32 left-sided breast cancer patients, with 16 having undergone breast-conserving surgery and 16 having undergone mastectomy. For each patient, 16 distinct VMAT plans were generated to compare combinations of optimization algorithms (FMO/SPO), fluence mod

SUBMITTER: Chen S 

PROVIDER: S-EPMC12781846 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature