Donor-derived membranous nephropathy in the allograft kidney: A rare but probably underestimated complication.

ABSTRACT: Transmitted donor-derived glomerular diseases in the allograft kidney are rare, especially when encountered in an allograft from a living donor. To date, only individual reports of donor-derived membranous nephropathy (MN) have been described. In this report, we present a case of MN discovered in a postreperfusion biopsy of a living-donor allograft. A follow-up biopsy 3 weeks later demonstrated persistent deposits. Thirteen months posttransplant, the recipient showed mildly worsening proteinuria but stable kidney function. To further our understanding of this exceedingly rare complication, we share our experience with 7 additional in-house cases together with 6 cases described in the literature to date. A minority of the donors were living. Most donors did not exhibit significant proteinur

SUBMITTER: Nuccitelli RA 

PROVIDER: S-EPMC12782192 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature