Microbial profile along the maternal-infant axis: Early characterization and relationships in breastfeeding women and their newborns in a Colombian population.

ABSTRACT:

Objective

To characterize the maternal-infant microbiota and examine microbial relationships among the maternal gut, human milk, and infant gut microbiomes in a cohort of Colombian mother-infant pairs at a single time point within the first three months postpartum.

Study design

A cross-sectional study was conducted with 30 mother-infant pairs. A total of 90 samples of human milk, maternal feces, and infant feces from healthy, exclusively breastfeeding pairs were analyzed to assess bacterial composition and diversity using microbiota analysis performed with 16S ribosomal RNA (rRNA) sequencing on the Illumina platform.

Results

The maternal gut microbiota was dominated by Subdoligranulum spp., Akkermansia spp., Christensenellaceae R-7 group, and Bacteroides spp., while t

SUBMITTER: Londono-Sierra DC 

PROVIDER: S-EPMC12782371 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature