Social determinants in the delay of starting colorectal cancer treatment.

ABSTRACT: Delayed access to colorectal cancer (CRC) treatment leads to disease progression, advanced stages at diagnosis, and reduced survival. In Brazil, Law 12.732/2012 mandates treatment initiation within 60 days of diagnosis; however, disparities persist. To assess compliance with the 60-day treatment initiation window for CRC in Brazil and its association with individual, socioeconomic, and healthcare system factors. We conducted a longitudinal observational retrospective cohort study using data from 65,582 CRC cases diagnosed between 2013 and 2019 in Brazil. Individual-level data were obtained from the Integrator of Hospital Cancer Registries, while socioeconomic and healthcare infrastructure data were extracted from national databases. A Multilevel Poisson Regression model with a random inter

SUBMITTER: Dantas AAG 

PROVIDER: S-EPMC12782427 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature