Expanding Lung Volume Reduction Surgery Indications: Outcomes in Patients Beyond Conventional National Emphysema Treatment Trial Criteria.

ABSTRACT:

Objectives

Lung volume reduction surgery (LVRS) is guided by strict selection criteria from the National Emphysema Treatment Trial (NETT) to minimize risk and optimize outcomes. However, emerging evidence suggests that rigid cutoffs may exclude patients who could benefit. This study aimed to identify beyond-criteria patients undergoing LVRS and compare their outcomes with standard-criteria patients.

Methods

This single-centre retrospective analysis of a prospectively maintained database included all LVRS procedures from August 2019 until November 2024. Patients were classified as beyond-criteria if they met two or more of the following: age ≥ 75 years, body mass index (BMI) < 18.5 kg/m2, forced expiratory volume in 1 second (FEV1) < 20%pred, diffusing capacity for carbon mon

SUBMITTER: Vandervelde CM 

PROVIDER: S-EPMC12782724 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature