Hokuriku-plus Heart Failure Registry Study　- Rationale and Study Design.

ABSTRACT:

Background

Heart failure (HF) is an increasing public health concern in Japan, largely related to the aging population. This protocol describes the rationale, objectives, and methods of the Hokuriku-plus Heart Failure Registry (HpHFR), designed to establish a comprehensive clinical and digital database to assess novel prognostic indicators in patients with HF.

Methods and results

HpHFR is a prospective, multicenter observational cohort study that has enrolled patients with acute or chronic HF from 5 Japanese centers. Eligible patients provided informed consent and underwent baseline clinical, laboratory, and biometric assessment, including digital phonocardiography and wearable device data. Follow-up assessment will be conducted at 4, 12, 26, and 52 weeks. Primary outcomes i

SUBMITTER: Takeji Y 

PROVIDER: S-EPMC12782937 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature