Relative contribution of three transporters to D-xylose uptake in <i>Aspergillus niger</i>.

ABSTRACT: The production of biofuels and chemicals from D-xylose is a promising option as D-xylose is the second most abundant sugar after D-glucose in lignocellulosic biomass. In microbes, efficient D-xylose uptake is a prerequisite for its utilization. Therefore, increasing D-xylose uptake efficiency by manipulation of D-xylose transporters would be an attractive strategy to improve fungal cell factories that use D-xylose as a substrate. In this study, we compared the contribution of three D-xylose transporters (XltA, XltB, XltD) from Aspergillus niger to overall D-xylose uptake at two D-xylose concentrations. XltA and XltD contributed similarly to D-xylose uptake, while the role of XltB was minimal. However, even in the absence of all three transporters, D-xylose uptake still occurred, ind

SUBMITTER: Meng J 

PROVIDER: S-EPMC12782949 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature