Association between serum lipids and colorectal polyps: a retrospective cross-sectional study.

ABSTRACT:

Background

The relationship between serum lipids and colorectal polyps (CP) remains unclear due to inconsistent findings across prior studies. This study aimed to comprehensively explore the relationship between serum lipid levels and CP risk by using real-world clinical data.

Methods

By utilizing retrospective data from a tertiary hospital from 2015 to 2024, multivariate logistic regression, restricted cubic spline (RCS), and subgroup analyses were performed to assess the association between serum lipids and CP. Additionally, the mediating role of inflammation-related indices in the relationship between serum lipids and CP was examined.

Results

Triglyceride (TG) and total cholesterol (TC) were positively associated with CP risk (P < 0.05). RCS analysis revealed a non

SUBMITTER: He M 

PROVIDER: S-EPMC12783160 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature