Clinical outcomes of drug-coated balloon vs. second-generation drug-eluting stent for coronary in-stent restenosis.

ABSTRACT:

Background

Current guideline recommendations for the treatment of coronary in-stent restenosis (ISR) are primarily based on evidence from smaller, randomized trials comparing drug-coated balloons (DCBs) and second-generation drug-eluting stents (DES).

Purpose

The purpose was to compare clinical outcomes between DCB and DES in routine clinical practice.

Methods

In this population-based cohort study, we identified 10,292 patients with ISR who underwent either DCB or DES intervention. After 1:1 propensity score matching, 3942 patients treated with either DCB or second-generation DES were included in the analysis. The composite primary end point was all-cause mortality or myocardial infarction (MI) at 1 year. Secondary end points included each component of the primary end

SUBMITTER: Krefting J 

PROVIDER: S-EPMC12783194 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature