Plaque and Salivary Fluoride Levels in Preschoolers Following Applications of Silver Diamine Fluoride, Sodium Fluoride Varnish, and Their Combination: A Randomized Clinical Trial.

ABSTRACT:

Background

The amount of fluoride maintained in the oral cavity aids in the remineralization process.

Hypothesis/aim

To evaluate and compare plaque and salivary fluoride levels following applications of silver diamine fluoride (SDF), sodium fluoride varnish (NaFV), or both.

Design

Sixty preschoolers randomly received 38% SDF, 5% NaFV, or both (SDF + NaFV). Plaque and saliva were collected at baseline; 5, 30, and 60 min; and 24 and 48 h post-application. Fluoride levels in plaque and saliva were evaluated and statistically compared (p < 0.05).

Results

Salivary fluoride levels peaked 5 min post-application in all groups and recovered to baseline within 1 to 24 h. Plaque fluoride levels peaked between 5 and 60 min, then returned to baseline within 1 to 24 h. The S

SUBMITTER: Asavalertpalakorn C 

PROVIDER: S-EPMC12783417 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature