Chest Computed Tomography Patterns Associated with Severity in Adults with Respiratory Syncytial Virus Infection: A Retrospective Cohort Study.

ABSTRACT:

Introduction

There are limited data available on the relationship between chest computed tomography (CT) patterns and clinical severity in adult patients infected with respiratory syncytial virus (RSV). It was hypothesized that specific CT patterns would be associated with distinct clinical outcomes and would correlate with both immune status and viral load.

Methods

We conducted a retrospective, single-center study of adults aged ≥ 18 years with laboratory-confirmed RSV infection and chest CT performed within 7 days of diagnosis. A blinded radiologist reviewed the CT patterns and scored them using the Chest CT Score (CCTS). Clinical severity was defined as World Health Organization (WHO) clinical progression scale ≥ 5 (hospitalized patients requiring oxygen). Multivariable l

SUBMITTER: Le Goff M 

PROVIDER: S-EPMC12783463 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature