Haemophilus influenzae and Staphylococcus aureus population shifts during social distancing as monitored by MALDI-TOF MS.

ABSTRACT: The COVID-19 pandemic prompted widespread public health interventions, including lockdowns and social distancing measures, which influenced microbial transmission dynamics. This study evaluates the evolution of the hospital incidence and spectral diversity of Haemophilus influenzae and Staphylococcus aureus associated with these measures using MALDI-TOF mass spectrometry-based epidemiological surveillance. MALDI-TOF MS spectra analyses of routine clinical bacterial identifications were used as proxies for strain typing. Spectra from lockdown and reference periods were compared using unsupervised classification methods. A total of 251 main spectrum profiles of H. influenzae, 2079 main spectrum profiles of S. aureus for respiratory tract and blood samples, and 414 main spectrum profiles for

SUBMITTER: Hmidi S 

PROVIDER: S-EPMC12783655 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature