Impact and cost-effectiveness of the community-led AMETHIST intervention among female sex workers in Zimbabwe.

ABSTRACT: Female sex workers (FSW) face high HIV risk of HIV transmission and acquisition. The AMETHIST ("Adapted Microplanning: Eliminating Transmissible HIV In Sex Transactions") trial enhanced Zimbabwe's Key Populations (KP) programme by providing targeted, community-based support for FSW. We used the HIV Synthesis Model to assess its long-term impact and cost-effectiveness. Given USAID's major role in funding, we also evaluated the effects of ending US support on the KP programme. We modelled a KP programme from 2010. From 2024 we compared (i) continuation of KP programme to (ii) continuation of KP programme + 'AMETHIST' intervention. We assessed HIV outcomes in 2030 and conducted cost-effectiveness analysis over a 50 year time horizon. Similar analyses were undertaken comparing continuation of

SUBMITTER: Bansi-Matharu L 

PROVIDER: S-EPMC12783726 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature