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AI-enabled electrocardiogram alert for potassium imbalance treatment: a pragmatic randomized controlled trial.


ABSTRACT: Life-threatening dyskalemia, defined as an abnormal serum potassium concentration, is common in emergency settings that requires timely recognition and treatment and can be detected via AI-enabled electrocardiography. We conducted a pragmatic, open-label, randomized controlled trial with physician-level randomization to evaluate whether a real-time AI-enabled electrocardiography alert could improve physicians' management of dyskalemia. Over a six-month period in 2022, 70 emergency physicians were randomized (35 intervention, 35 control) and provided care to 14,989 patients (7506 in the intervention group and 7483 in the control group) at an academic medical center and a community hospital (ClinicalTrials.gov NCT05118022). The trial had two primary outcomes: the rate of hyperkalemia-related

SUBMITTER: Lin C 

PROVIDER: S-EPMC12783823 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature