Silver and polystyrene nanoparticles activate oestrogen signalling via cytoplasmic oestrogen receptor.

ABSTRACT: This study explores the endocrine-disrupting potential of two commonly encountered nanomaterials, nanoplastic and silver nanoparticles (AgNPs). Many environmental pollutants, especially endocrine-disrupting chemicals (EDCs), such as bisphenol, heavy metals, interfere with hormone function, posing a serious risk for public health, e.g. prevalence of breast cancer, whose incidence correlates strongly with EDC exposure. However, the impact on hormonal homeostasis of many environmental contaminants, such as nanoplastic, is still unknown. Nanoplastic is a product of the weathering process of plastic goods, while AgNPs are released to the environment from everyday use items, such as health care products, food-related materials or medical devices. These nanoparticles penetrate biological barriers

SUBMITTER: Lekki-Porebski SA 

PROVIDER: S-EPMC12783835 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature