Cosmetic Botulinum Toxin A Injections to the Upper Face: A Systematic Review and Meta-Analysis of Clinical Studies.

ABSTRACT:

Background

Botulinum toxin type A (BoNT-A) is widely recognized as the leading nonsurgical cosmetic treatment worldwide for diminishing dynamic wrinkles in the glabellar, forehead, and periorbital areas. While BoNT-A is widely acknowledged for its effectiveness and popularity, there are notable inconsistencies in results, methodologies, and safety reporting across clinical studies, highlighting the necessity for the careful development of strong, evidence-driven guidelines.

Objectives

This study aimed to compile and evaluate data from clinical research focusing on upper-face BoNT-A injections, specifically regarding safety outcomes, effectiveness, patient satisfaction, and response rates. This investigation concentrated on the outcomes of the clinical trials conducted.

Me

SUBMITTER: Safia A 

PROVIDER: S-EPMC12783872 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature